Optical stimulation of LS Purkinje cells alters mPFC-dCA baseline coherence across different frequency bands. The baseline coherence was calculated for each frequency band by averaging time-resolved mPFC-dCA1 coherence during the initial 0.5 s after mice entered the center area with all four paws. LS Purkinje cell optical stimulation reduced baseline coherence for LFP oscillations in the theta (4–8 Hz), alpha (8–12 Hz), beta (12–30 Hz), low-gamma (30–60 Hz), and mid-gamma (60–80 Hz) bands and increased baseline coherence for oscillations in the high-frequency (100–130 Hz), and very high-frequency (130–200 Hz) bands. LS Purkinje cell stimulation had no effect on baseline coherence in the high-gamma (80–100 Hz)-frequency band. Two-sample t tests were used to compare the differences between control and LS stimulation trials for each frequency band. Data were expressed as mean ± standard error. **p < 0.01; ***p < 0.001