Table 6.

Lymphocytopenia adverse events in simulated “clarity extension” – sub-cohort a – RCT.

Grade (*)	CP 3.5 mg/kg (n = 300)	CP 5.25 mg/kg (n = 300)	CC 7 mg/kg (n = 300)	CC 8.75 mg/kg (n = 300)	PC 3.5 mg/kg (n = 300)
1
2
3	16	20	115	150	73
4	0	0	8	10	2

(*) grade 1: absolute lymphocytes count (ALC) 800–999/μl; grade 2: ALC 500–799/μl; grade 3: ALC 200–499/μl; and grade 4: ALC< 200/μl [40].