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. 2023 May 17;14:973930. doi: 10.3389/fendo.2023.973930

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Copyright © 2023 Zhao, Jiang, Luo, Zhao and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein-protein interaction analysis on DEGs at maternal-fetal interface. PPI network of DSC-DEGs (A), placenta-DEGs (B) and macrophages polarization DEGs (C). The PPI network of hub genes (D), in which the diamonds, the rectangles and the “V”-shape nodes represented hub genes from DSC-DEGs, from macrophages polarization DEGs, and from placenta-DEGs, respectively. The functions of the hub proteins were predicted by the GeneMANIA plug-in in Cytoscape (E). The qRT-PCR results of DSC-DEGs (F), placenta-DEGs (G) and macrophages polarization DEGs (H). * represents P<0.05, **represents P<0.01, compared with the control group.