Table 4.
The physicochemical properties of the reported hub proteins.
| Name | Number of Amino Acids |
Molecular Weight (kda) |
Theoretical pI | Number of Negatively Charged Residues(Asp + Glu) |
Number of Positively Charged Residues(Arg + Lys) |
Extinction Coefficient |
Instability Index |
Aliphatic Index |
Grand Average of Hydropathicity (GRAVY) |
Classification |
|---|---|---|---|---|---|---|---|---|---|---|
| MMP1 | 469 | 54006.90 | 6.47 | 58 | 54 | 76905 | 35.46 | 65.27 | -0.572 | DSCs |
| COL12A1 | 3063 | 333146.77 | 5.38 | 366 | 313 | 334620 | 32.90 | 75.45 | -0.427 | DSCs |
| MET | 1390 | 155541.31 | 7.02 | 137 | 134 | 127070 | 42.61 | 88.02 | -0.144 | DSCs |
| MMP7 | 267 | 29676.84 | 7.73 | 28 | 29 | 44015 | 32.39 | 76.37 | -0.369 | DSCs |
| TNFRSF11B | 401 | 46026.02 | 8.66 | 42 | 53 | 50890 | 49.09 | 74.84 | -0.483 | DSCs |
| C3 | 1663 | 187148.06 | 6.02 | 213 | 195 | 180055 | 42.47 | 87.87 | -0.320 | Decidua macrophage |
| CFB | 764 | 85532.87 | 6.67 | 94 | 91 | 122170 | 43.55 | 75.09 | -0.501 | Decidua macrophage |
| SERPING1 | 500 | 55154.19 | 6.09 | 48 | 43 | 27180 | 33.71 | 89.70 | -0.125 | Decidua macrophage |
| CP | 3785 | 311348.49 | 4.82 | 0 | 0 | 47000 | 48.21 | 32.66 | 0.817 | Decidua macrophage |
| CFI | 583 | 65750.26 | 7.72 | 67 | 70 | 101405 | 38.53 | 70.53 | -0.321 | Decidua macrophage |
| CXCL8 | 99 | 11098.12 | 9.10 | 11 | 16 | 7240 | 24.95 | 101.52 | -0.019 | Placenta |
| SERPINA1 | 418 | 46736.55 | 5.37 | 56 | 41 | 25565 | 31.65 | 91.20 | -0.183 | Placenta |
| FCGR3B | 233 | 26215.86 | 6.22 | 21 | 18 | 46660 | 40.91 | 90.73 | -0.080 | Placenta |
| S100A8 | 93 | 10834.51 | 6.50 | 15 | 14 | 11460 | 25.04 | 96.45 | -0.397 | Placenta |
| LTF | 710 | 78181.95 | 8.50 | 79 | 90 | 88290 | 44.28 | 74.62 | -0.337 | Placenta |
*Extinction coefficients are in units of M-1 cm-1 , at 280 nm measured in water.