FIG 4.

Evaluating compound structure-activity relationship for anti-PRRSV infection. (A) Molecular structures of B7 and B7-A4 analogues. (B) qRT-PCR for PRRSV in total RNAs extracted from infected PAMs treated with B7 and B7-A4 analogues. Values are normalized with GAPDH of PAMs. Bars = mean ± SD; n = 3. P values are calculated by one-way ANOVA, and letters on the top of bars indicate significant differences in Tukey post hoc test. (C) Titration assay results for PRRSV in the culture media of PAMs treated as described in panel B. Bars = mean ± SD; n = 3. P values are calculated by one-way ANOVA, and letters on the top of bars indicate significant differences in Tukey post hoc test.