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. Author manuscript; available in PMC: 2023 May 31.
Published in final edited form as: Dev Biol. 2022 Oct 2;492:111–118. doi: 10.1016/j.ydbio.2022.09.012

Fig. 5.

Fig. 5.

Predicted Foxc1 binding site is required for heart and kidney expression in adults. The intact enhancer drove robust GFP reporter gene expression in the adult heart (A), with overall stronger expression present in the atrium than ventricle. At the same exposure time (139 ms) used for the intact transgene, no heart expression was detected for either the scrambled (B) or deleted (C) constructs (but see Fig. S3). The intact enhancer also drove robust GFP expression in renal corpuscles (arrowhead) of the kidney (D). This domain was severely reduced for the scrambled construct (E) and not detectable for the deleted construct (F). Abbreviations: a = atrium, v = ventricle. Scale bars = 1 mm (A–C), 200 μm (D–F).