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. 2023 May 26;29:e20220079. doi: 10.1590/1678-9199-JVATITD-2022-0079

Table 2. Plant organ and phytoproducts concentration of phytoproducts Moringa oleifera for i n vivo and in vitro antimalarial activity.

Plant organ Product Concentration or dose Strain Method References
Leaves Acetone extract 200, 400 and 600 mg/kg Plasmodium berghei In vivo [ 39]
Leaves Hexane extract, methanol extract, aqueous extract 6.25, 12.5, 25 and 50 µg/mL Plasmodium falciparum (3D7) In vitro [ 40]
Leaves Aqueous extract, ethanol extract 100, 200, 400 and 800 mg/kg Plasmodium berghei In vivo [ 41]
Seed Ethanol extract 200, 300 and 500 mg/kg Plasmodium berghei In vivo [ 42]
Leaves Pellets 30 and 60 mg/mouse Plasmodium chabaudi In vivo [ 43]
Seed Oil 200, 400 and 800 mg/kg Plasmodium berghei (NK65) In vivo [ 44]
Leaves Aqueous extract 250, 500, 750 and 1000 mg/kg Plasmodium berghei (NK65) In vivo [ 69]
Leaves Aqueous extract 100, 500 and 1000 mg/kg Plasmodium berghei (ANKA) In vivo [ 70]
Leaves Aqueous extract 500, 1000 and 2000 mg/kg Plasmodium berghei (ANKA) In vivo [ 71]
Leaves Aqueous extract 100, 500 and 1000 mg/kg Plasmodium berghei (ANKA) In vivo [ 72]
Flowers, leaves, stems Lipophilic extract, methanol extract 6 and 25 µg/mL Plasmodium falciparum In vitro [ 73]
Leaves Methanol extract and its fractions 50 and 100 mg/kg Plasmodium berghei (NK65) In vivo [ 74]
Leaves Aqueous extract 100, 1000 and 2000 mg/kg Plasmodium berghei (ANKA) In vivo [ 75]
Leaves n-Hexane extract, ethanol extract 50, 100 and 200 mg/kg Plasmodium berghei In vivo [ 76]
Flowers, leaves Methanol extract 125, 250, 500 and 1000 mg/kg Plasmodium yoelii (N-67) In vivo [ 77]
Seed n-Hexane extract, ethanol extract 50, 100 and 200 mL/kg Plasmodium berghei In vivo [ 110]
Leaves Bioactive fraction 100, 150 and 200 mg/kg Plasmodium berghei Q (N1923) In vivo [ 111]
Leaves Aqueous extract 150 mg/kg Plasmodium yoelii In vivo [ 112]
Leaves Infusion 100, 200 and 400 mg/kg Plasmodium berghei (ANKA) In vivo [ 113]