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. 2021 Feb 22;24(4):131–136. doi: 10.1136/ebmental-2020-300232

Figure 2.

Figure 2

Screenshot of the required fields and the resulted table for estimation of the NNT in survival analysis using the Cox regression model. The adjusted value is the baseline PANSS Score that is set to 100, and the timepoint is set to seven (7 months). Note that for the survival analysis, the calculations may take some time. NNT-KM(7), the Kaplan-Meier-based non-parametric maximum likelihood estimator of the unadjusted NNT for time point 7. NNT-COX(7), Cox regression-based estimator of the marginal NNT for timepoint 7. NNT(7|100), Cox regression-based estimator of the adjusted NNT for timepoint 7 and covariate value of 100. CI DL L, the lower limit of the 95% level delta-method-based CI; CI DL U, the upper limit of the 95% level delta-method-based CI; CI NBS L, lower limit of the 95% level non-parametric-bootstrap-based CI; CI NBS U, the upper limit of the 95% level non-parametric-bootstrap-based CI; CI PBS L, the lower limit of the 95% level parametric-bootstrap-based CI; CI PBS U, the upper limit of the 95% level parametric-bootstrap-based CI; For the unadjusted NNT point estimator, the PBS-based CI limits are not available (NA) since the NNT-KM is a non-parametric estimator. CI TR L, the lower limit of the 95% level transformation-based CI; CI TR U, the upper limit of the 95% level transformation-based CI; MCID, minimally clinically important difference; NNT, number needed to treat; PANSS, Positive and Negative Syndrome Scale. ANOVA, analysis of variance. group ID, group identifier. Inf, Infinity,