Table I.
Fourteen proteins in fetal bovine serum commonly depleted charcoal-stripping.
| Protein name | Gene name | Relative ratios | MW (kDa) /pI | GO-Cellular Component | Cell Proliferation Related Reports | References | ||
|---|---|---|---|---|---|---|---|---|
| FBS/ HCS1 | FBS/ HCS2 | FBS/ CCS | ||||||
| Protein-lysine 6-oxidase | LOX | 46.1 | 55.2 | 60.7 | 29/5.9 | Extracellular region | Stimulator | Shih YH et al., Head Neck 2013, 35: 250–256. |
| Complement factor D | CFD | 8.0 | 13.6 | 3.4 | 25/6.9 | Extracellular region | Stimulator | Corrales L et al., J Immunol 2012, 189: 4674–4683. |
| Peptidoglycan recognition protein 1 | PGLYRP1 | 7.1 | 9.2 | 1.5 | 19/9.4 | Extracellular region | Stimulator | De Marzi MC et al., Immunology 2015, 145: 429–442. |
| Insulin-like growth factor-binding protein 2 | IGFBP2 | 6.2 | 5.5 | 3.3 | 31/6.9 | Extracellular region | Stimulator | Han S et al., Br J Cancer 2014, 111: 1400–1409. |
| Thymosin beta-10 | TMSB10 | 5.4 | 4.1 | 4.0 | 5/6.5 | Cytoplasm | Inhibitor | Lee SH et al., Cancer Res 2005, 65: 137–148. |
| Beta-2- microglobulin | B2M | 5.4 | 5.6 | 3.4 | 12/8.0 | Extracellular region | Stimulator/ Inhibitor | Min R et al., Br J Haematol 2002, 118: 495–505; Li Let al., Chin Med J (Engl) 2016, 129:448–455. |
| Apolipoprotein C-III | APOC3 | 5.3 | 3.3 | 2.8 | 8/4.7 | Extracellular region | Stimulator | Li H et al., Cardiovasc Res. 2015, 107: 579–589. |
| Insulin-like growth factor-binding protein 6 | IGFBP6 | 5.3 | 5.1 | 9.0 | 22/8.5 | Extracellular region | Inhibitor | Kim EJ et al., J Cell Physiol 2002, 190: 92–100. |
| Regakine-1 | N/A | 5.3 | 6.1 | 3.9 | 8/8.8 | Extracellular region | N/A | N/A |
| Fibrinogen alpha chain | FGA | 3.6 | 3.7 | 5.6 | 2/7.7 | Extracellular region | Stimulator | Palumbo JS et al., Blood 2000, 96: 3302–3309. |
| Profilin-1 | PFN1 | 3.0 | 3.0 | 3.9 | 15/8.5 | Extracellular region | Inhibitor | Zou L et al., J Cell Physiol 2010, 223: 623–9. |
| Insulin-like growth factor II | IGF2 | 2.9 | 4.6 | 6.3 | 8/6.4 | Extracellular region | Stimulator | Pollak M et al., Nat Rev Cancer 2008, 8: 915–928. |
| Hemoglobin subunit beta | HBB | 1.8 | 1.8 | 2.7 | 16/7.0 | Extracellular region | Inhibitor | Maman S et al., Cancer Res 2017, 77: 14–26. |
| Secreted phosphoprotein 24 | SPP2 | 1.5 | 1.5 | 1.6 | 20/7.9 | Extracellular region | Inhibitor | Lao L et al., Anticancer Res 2016, 36: 5773–5780. |