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. 2023 Apr 27;14(3):330–341. doi: 10.4103/idoj.idoj_355_22

Table 3.

Definitions of endpoint of treatment for onychomycosis being used in the literature

Endpoint of therapy Definition
Mycological cure (MC) Negative microscopy and culture (on 2 consecutive occasions, 4-weeks apart)
Clinical cure (CC) Complete absence of all lesions on each nail (based on sequential photographs) OR Residual disease, which is <10% of original disease surface
Complete cure Both mycological and clinical cure
Clinical improvement Reduction in total affected nail area which is >20% compared to baseline