Table I.
Antibody levels and seropositivity rate for spike and nucleocapsid proteins in different participant groups
| Parameters | Study participant (n) | Nucleocapsid | Spike | P value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Number of positive | Per cent positive | Reactivity | Number of positive | Per cent positive | Reactivity | |||||||
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| Mean | SD | 95% CI | Mean | SD | 95% CI | |||||||
| Total | 132 | 95 | 72.0 | 12.8 | 10.9 | 11.0-15.0 | 73 | 55.3 | 4.8 | 1.8 | 4.4-5.2 | <0.001 |
| Males | 73 | 55 | 75.3 | 14.5 | 11.6 | 11.4-17.7 | 47 | 64.4 | 5.1 | 1.9 | 4.5-5.6 | <0.001 |
| Females | 59 | 40 | 67.8 | 10.4 | 9.5 | 7.3-13.3 | 26 | 44.1 | 4.2 | 1.4 | 3.6-4.7 | <0.001 |
| Symptomatic | 90 | 65 | 72.2 | 14.9 | 12.0 | 12.0-17.9 | 44 | 48.9 | 5.0 | 1.9 | 4.5-5.6 | <0.001 |
| Asymptomatic | 42 | 30 | 71.4 | 8.1 | 5.9 | 5.9-10.3 | 29 | 69.0 | 4.4 | 1.6 | 3.8-5.0 | 0.006 |
| ICU | 28 | 23 | 82.1 | 18.7 | 13.5 | 12.8-24.5 | 17 | 60.7 | 5.8 | 1.6 | 5.0-6.6 | 0.02 |
| Ward | 104 | 72 | 69.2 | 10.9 | 9.2 | 8.7-13.1 | 56 | 53.8 | 4.4 | 1.7 | 4.0-5.0 | <0.001 |
| Adults | ||||||||||||
| ICU | 16 | 14 | 87.5 | 22.5 | 11.5 | 15.9-29.1 | 13 | 81.3 | 6.3 | 1.2 | 5.6-7.1 | 0.01 |
| Ward | 43 | 31 | 72.1 | 15.3 | 11.2 | 11.2-19.4 | 22 | 51.2 | 4.3 | 1.6 | 3.6-5.1 | <0.001 |
| Children | ||||||||||||
| ICU | 12 | 9 | 75.0 | 12.7 | 14.9 | 1.2-24.2 | 4 | 33.3 | 4.2 | 1.5 | 1.8-6.6 | 0.15 |
| Ward | 61 | 41 | 67.2 | 7.6 | 5.6 | 5.8-9.3 | 34 | 55.7 | 4.5 | 1.8 | 3.8-5.1 | 0.016 |
Only the samples with reactivity ≥2-fold of the naive control were considered positive for reactivity with the proteins. P values represent the significance of the difference in reactivity between spike and nucleocapsid, SD represents variation within the group and the higher and lower limits of confidence interval are at 95% CI. SD, standard deviation; ICU, intensive care unit; CI, confidence interval