Table 2.
Demographics of SVA positive men
| Total (n = 36) | Symptomatic men (n = 29) | Asymptomatic men (n = 7) | Z statistic | P-value | |
|---|---|---|---|---|---|
| Age at onset, median (IQR) | 39 (32–46) | 39 (32–46) | N/A | ||
| Age at exam, median (IQR) | 38 (30–48.5) | 43 (34–51) | 29 (25–34) | −3.04 | 0.002 |
| Disease duration at enrollment (years) median, (IQR) | 4 (2–5) | 4 (2–5) | N/A | ||
| TAF1 repeat size | 42.5 (40.5–47) | 42 (39–47) | 43 (42–50) | 1.11 | 0.27 |
| Initial symptom | |||||
| Dystonia (n) | 23 | 23 | N/A | ||
| Parkinsonism (n) | 6 | 6 | N/A |
The average age of all gene-positive men, at enrollment, was 39.9 years (+11.01, n = 36) compared to 36.18 years in the gene-negative cohort (+12.56, n = 51). IQR: interquartile range, N/A: Not Applicable.