Table 4.
Symptomatic men (n = 29) | Asymptomatic men (n = 7) | |||||||
---|---|---|---|---|---|---|---|---|
Variable | Baseline | Month 6 | Month 12 | Month 18 | Baseline | Month 6 | Month 12 | Month 18 |
Clinician-rated | ||||||||
Nutritional state | ||||||||
BMI | ||||||||
Mean (SD) | 21.53 (3.69) | 20.00 (3.56) | 19.12 (3.36) | 18.52 (3.07) | 23.31 (5.05) | 24.56 (3.98) | 21.59 (4.44) | 22.67 (3.24) |
Min–Max | 16.84–26.26 | 14.47–27.07 | 13.87–26.67 | 14.09–25.68 | 17.45–29.26 | 18.19–27.95 | 16.82–25.71 | 20.34–24.96 |
Missing | 22 | 2 | 6 | 4 | 3 | 1 | 3 | 5 |
Swallow mechanism | ||||||||
Lip strength | ||||||||
Mean (SD) | 13.31 (6.79) | 13.01 (5.46) | 11.13 (4.84) | 16.59 (7.57) | 27.33 (7.36) | 24 (7.27) | 32.17 (0.71) | 32 (10.84) |
Min–Max | 1.67–30 | 2–21.3 | 3.67–17.67 | 4.33–33.67 | 20.33–35 | 15.67–32 | 31.67–32.67 | 24.33–39.67 |
Missing | 5 | 5 | 13 | 8 | 4 | 2 | 5 | 5 |
Tongue strength | ||||||||
Mean (SD) | 32.34 (17.77) | 33.58 (14.79) | 30.96 (16.09) | 30.55 (15.19) | 61.33 (7.23) | 51.73 (8.21) | 67.34 (4.72) | 53 (19.80) |
Min–Max | 4.67–65 | 10.67–61.67 | 9.33–57.33 | 8–57.67 | 53–66 | 42.33–64.67 | 64–70.67 | 39–67 |
Missing | 5 | 3 | 12 | 7 | 4 | 2 | 5 | 5 |
Swallow duration | ||||||||
Mean (SD) | 8.87 (7.56) | 7.25 (4.84) | 10.51 (6.66) | 12.06 (9.07) | 2.33 (0.32) | 2.86 (0.63) | 2.22 (0.33) | 2.97 (0.65) |
Min–Max | 0.7–31 | 2.3–25.03 | 2.83–28 | 3.1–37.7 | 2–2.64 | 2.38–3.89 | 1.98–2.45 | 2.51–3.43 |
Missing | 5 | 5 | 15 | 10 | 4 | 2 | 5 | 5 |
Communication ability | ||||||||
SMR BA rate | ||||||||
Mean (SD) | 5.21 (1.17) | 5.17 (1.07) | 5.05 (1.19) | 4.56 (1.29) | 6.02 (0.32) | 6.28 (0.45) | 4.41 (1.2) | 4.01 |
Min–Max | 2.7–7.4 | 2.8–7.2 | 2.98–6.97 | 2.37–6.65 | 5.72–6.35 | 5.8–7.0 | 3.43–6.4 | 4.01 |
Missing | 14 | 10 | 12 | 18 | 4 | 2 | 2 | 6 |
SMR DA rate | ||||||||
Mean (SD) | 5.11 (1.66) | 4.73 (1.28) | 4.57 (1.55) | 3.94 (1.79) | 6.57 (0.28) | 6.56 (0.55) | 5.4 (1.82) | 3.9 |
Min–Max | 2.1–8.1 | 2.4–6.5 | 2.23–6.84 | 1.23–6.11 | 6.3–6.85 | 6–7.4 | 3.76–7.65 | 3.9 |
Missing | 15 | 9 | 12 | 18 | 6 | 4 | 4 | 8 |
SMR KA rate | ||||||||
Mean (SD) | 4.74 (1.20) | 4.93 (1.61) | 5.03 (2.02) | 4.07 (1.63) | 5.83 (0.51) | 5.9 (0.57) | 4.98 (1.55) | 3.64 |
Min–Max | 2.6–6.9 | 2.6–8.8 | 1.98–8.83 | 1.37–6.42 | 5.25–6.2 | 5.4–6.8 | 3.25–6.78 | 3.64 |
Missing | 16 | 13 | 12 | 18 | 6 | 4 | 4 | 8 |
AMR rate | ||||||||
Mean (SD) | 1.98 (0.40) | 1.71 (0.32) | 1.82 (0.56) | 1.70 (0.54) | 2.41 (0.45) | 2.22 (0.15) | 2.47 (0.16) | 1.92 |
Min–Max | 1.25–2.6 | 1.1–2.4 | 0.75–2.78 | 0.64–2.41 | 1.9–2.75 | 2–2.4 | 2.25–2.66 | 1.92 |
Missing | 14 | 9 | 13 | 18 | 4 | 2 | 2 | 6 |
MDS-UPDRS Part III | ||||||||
Mean (SD) | 39.86 (18.21) | 35.38 (16.57) | 36.27 (11.84) | 51.04 (20.73) | 8 (9.26) | 3.6 (5.37) | 2.25 (2.63) | 2.5 (0.71) |
Min–Max | 10–90 | 3–80 | 8–53 | 0–92 | 2–27 | 0–13 | 0–6 | 2–3 |
Missing | 0 | 3 | 6 | 4 | 0 | 2 | 3 | 5 |
BFM movement | ||||||||
Mean (SD) | 24.21 (23.96) | 27.83 (26.00) | 28.68 (23.61) | 43.96 (28.31) | 0.57 (1.51) | 0 | 0.25 (0.5) | 0 |
Min–Max | 0–96 | 0–91 | 1.5–88 | 3–92 | 0–4 | 0 | 0–1 | 0 |
Missing | 0 | 3 | 7 | 4 | 0 | 2 | 3 | 5 |
SD—standard deviation