TABLE 2. Mpox incidence* among persons aged 15–64 years, by month† and urban-rural classification§ of county of residence — United States, May 10–December 31, 2022.
| Urban-rural classification | Incidence, by month |
Overall risk ratio (95% CI)** | |||||
|---|---|---|---|---|---|---|---|
| May–Jun | Jul¶ | Aug¶ | Sep¶ | Oct–Dec¶ | Overall | ||
|
All areas
|
0.5
|
4.2
|
5.3
|
2.3
|
1.3
|
13.5
|
— |
|
Urban
| |||||||
| Large central urban |
1.3 |
10.0 |
11.7 |
4.9 |
2.6 |
30.6
|
Ref |
| Large fringe urban |
0.3 |
2.9 |
3.9 |
1.6 |
1.0 |
9.7
|
0.32 (0.31–0.33) |
| Medium urban |
0.1 |
1.0 |
1.9 |
1.1 |
0.7 |
4.9
|
0.16 (0.15–0.17) |
| Small urban |
0.1 |
0.6 |
1.0 |
0.7 |
0.5 |
2.8
|
0.09 (0.08–0.10) |
|
Rural
| |||||||
| Nonmetropolitan | 0 | 0.3 | 0.6 | 0.4 | 0.2 | 1.5 | 0.05 (0.05–0.06) |
Abbreviation: Ref = reference group.
* Cases per 100,000 population, calculated using summed case counts and population size (persons aged 15–64 years) for all areas and for each level of urbanicity, multiplied by 100,000.
† Incidence during May–June and during October–December was combined because case counts were low during those periods.
§ Urban-rural classification of county of residence is based on the 2013 National Center for Health Statistics Urban-Rural Classification Scheme for Counties. The two nonmetro categories were combined into one rural (i.e., nonmetropolitan) category. Among the 29,311 cases reported in 2022, 135 were missing data on county of residence; therefore, incidences were calculated based on a total of 29,176 mpox cases.
¶ The number of cases in each period (numerator) was subtracted from the denominator for the following period when calculating incidence.
** Risk ratio was calculated by comparing large fringe urban, medium urban, small urban, and rural (nonmetropolitan) areas with large central urban areas.