Figure 4.

Effects of chrysin on sevoflurane anesthesia-induced oxidative stress in hippocampus of aged rats. Levels of MDA (A), NADPH oxidase activity (B), HNE levels (C) and GSH activity (D) in hippocampus among different groups were measured. N=10 rats for each group. Data were presented with mean±standard deviation. Brown-Forsythe ANOVA followed Dunn’s multiple comparisons test. ^*p<0.05; ^**p<0.01; ^***p<0.001. MDA, malondialdehyde; NADPH, nicotinamide adenine dinucleotide phosphate; HNE, hydroxynonenal; GSH, glutathione; Sev, sevoflurane; Ch25, chrysin 25 mg/kg/day; Ch50, chrysin 50 mg/kg/day; Ch100, chrysin 100 mg/kg/day.