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. 2023 Mar 2;12(2):164–174. doi: 10.12997/jla.2023.12.2.164

Table 2. Number, incidence rate, and hazard ratio for cardiovascular events (myocardial infarction or stroke) Stratified by non-HDL and LDL cholesterol.

Variables No. of patients No. of event Duration, person-years Rate, events per 1,000 person-years Non-adjusted Model 1 Model 2
Non-HDL cholesterol
Q1 959,579 14,927 8,773,254 1.70 1 (Ref.) 1 (Ref.) 1 (Ref.)
Q2 986,931 19,105 9,038,909 2.11 1.242 (1.215–1.269) 1.050 (1.027–1.072) 1.074 (1.051–1.097)
Q3 965,906 23,255 8,835,420 2.63 1.547 (1.515–1.579) 1.174 (1.150–1.199) 1.188 (1.164–1.213)
Q4 953,950 31,226 8,684,464 3.60 2.113 (2.072–2.155) 1.491 (1.462–1.520) 1.456 (1.427–1.486)
p for trend <0.001 <0.001 <0.001
LDL cholesterol
Q1 976,661 19,187 8,904,531 2.15 1 (Ref.) 1 (Ref.) 1 (Ref.)
Q2 975,502 18,776 8,936,121 2.10 0.974 (0.955–0.994) 0.942 (0.923–0.961) 1.008 (0.988–1.029)
Q3 934,272 21,091 8,553,002 2.47 1.144 (1.121–1.166) 1.008 (0.988–1.028) 1.091 (1.069–1.113)
Q4 979,931 29,459 8,938,393 3.30 1.528 (1.501–1.556) 1.196 (1.174–1.218) 1.281 (1.257–1.306)
p for trend <0.001 <0.001 <0.001

Model 1: adjusted for age and sex.

Model 2: adjusted for age and sex, alcohol consumption, regular physical activity, body mass index, diabetes, hypertension, and statin use.

HDL, high-density lipoprotein; LDL, low-density lipoprotein.