Table 5. Characteristics of coronary computed tomographic angiography stratified by tertiles of the Lp(a) and AIP.
| Variables | Total patients (n=625) | Tertile 1 of the AIP <0.209 (n=208) | Tertile 2 of the AIP 0.209–0.485 (n=209) | Tertile 3 of the AIP >0.485 (n=208) | p-value | Total patients (n=625) | Tertile 1 of the Lp(a) <6.6 (n=207) | Tertile 2 of the Lp(a) 6.6–18.9 (n=206) | Tertile 3 of the Lp(a) >18.9 (n=210) | p-value |
|---|---|---|---|---|---|---|---|---|---|---|
| CACS | 194.3±573.0 | 134.7±415.7 | 189.4±586.7 | 258.9±680.7 | 0.086 | 194.3±573.0 | 188.3±540.4 | 169.7±473.9 | 218.9±682.5 | 0.677 |
| CACS >0 | 312 (49.9) | 90 (43.3) | 113 (54.1) | 109 (52.4) | 0.060 | 312 (49.9) | 99 (47.8) | 91 (44.2) | 120 (57.1) | 0.024 |
| CACS ≥400 | 83 (13.3) | 21 (10.1) | 22 (10.5) | 40 (19.2) | 0.008 | 83 (13.3) | 28 (13.5) | 26 (12.6) | 28 (13.3) | 0.960 |
| CAC percentile | 32.5±38.1 | 27.4±36.0 | 33.0±36.6 | 37.0±41.0 | 0.037 | 32.5±38.1 | 32.9±38.5 | 29.9±38.3 | 34.0±37.3 | 0.528 |
| ≥90th percentile | 77 (12.3) | 15 (7.2) | 21 (10.0) | 41 (19.7) | <0.001 | 77 (12.3) | 28 (13.5) | 26 (12.6) | 22 (10.5) | 0.620 |
| CAC volume (mm3) | 155.1±452.0 | 110.4±334.5 | 147.8±459.6 | 207.0±535.6 | 0.089 | 155.1±452.0 | 151.2±421.3 | 136.6±378.4 | 172.6±539.0 | 0.716 |
| CAC mass (mg) | 39.1±123.8 | 29.0±101.0 | 34.8±117.6 | 53.4±147.6 | 0.110 | 39.1±123.8 | 38.1±114.7 | 36.2±112.1 | 41.6±142.2 | 0.901 |
| Presence of plaque | 393 (62.9) | 114 (54.8) | 136 (65.1) | 143 (68.8) | 0.010 | 393 (62.9) | 131 (63.3) | 122 (59.2) | 138 (65.7) | 0.385 |
| Multivessel disease | 59 (9.4) | 9 (4.3) | 22 (10.5) | 28 (13.5) | 0.005 | 59 (9.4) | 13 (6.3) | 19 (9.2) | 26 (12.4) | 0.100 |
| Revascularization | 79 (12.7) | 15 (7.2) | 25 (12.0) | 39 (18.8) | 0.002 | 79 (12.7) | 21 (10.1) | 27 (13.1) | 31 (14.8) | 0.357 |
Data are given as mean±standard deviations, or as number (%).
Lp(a), lipoprotein(a); AIP, atherogenic index of plasma; CACS, coronary artery calcium score; CAC, coronary artery calcium.