Table 2.

Classification performance between clinical subgroups in individual-specific/atlas-based functional connectivity.

		SVM Classification	AUC	ACC	SEN	SPE
APOE ε4 carriers (N = 120)	Individual-specific FC	NA vs. MCI	0.94	0.88	0.92	0.85
		MCI vs. AD	0.92	0.87	0.73	0.94
		NA vs. AD	0.94	0.90	0.92	0.85
	Atlas-based FC	NA vs. MCI	0.90	0.82	0.94	0.65
		MCI vs. AD	0.86	0.75	0.70	0.80
		NA vs. AD	0.92	0.88	0.90	0.80
APOE ε4 noncarriers (N = 115)	Individual-specific FC	NA vs. MCI	0.92	0.84	0.98	0.64
		MCI vs. AD	0.89	0.81	0.50	1.00
		NA vs. AD	0.96	0.89	0.94	0.82
	Atlas-based FC	NA vs. MCI	0.90	0.83	0.96	0.64
		MCI vs. AD	0.89	0.81	0.50	1.00
		NA vs. AD	0.96	0.87	0.94	0.78

Individual-specific FC Individual-specific functional connectivity, Atlas-based FC Atlas-based functional connectivity.