Table 3.
Multivariate regression models demonstrating baseline predictors of the neutrophil-to-lymphocyte and lymphocyte-to-monocyte ratios.
Regression coefficient [95% CI] | p-value | |
---|---|---|
Neutrophil-to-lymphocyte ratio | ||
Age | 0.023 [0.015, 0.031] | < 0.001* |
Male | 0.15 [0.036, 0.27] | 0.01* |
Years of education | 0.020 [− 0.00085, 0.040] | 0.06 |
Mild cognitive impairment | 0.16 [0.024, 0.30] | 0.021* |
Alzheimer’s disease | 0.35 [0.18, 0.53] | < 0.001* |
APOE ε2 allele | − 0.097 [− 0.32, 0.13] | 0.40 |
APOE ε4 allele | 0.19 [0.066, 0.31] | 0.003* |
Lymphocyte-to-monocyte ratio | ||
Age | − 0.033 [− 0.049, − 0.017] | < 0.001* |
Male | − 0.75 [− 0.98, − 0.52] | < 0.001* |
Years of education | − 0.038 [− 0.078, 0.0029] | 0.069 |
Mild cognitive impairment | − 0.36 [− 0.63, − 0.081] | 0.011* |
Alzheimer’s disease | − 0.43 [− 0.78, − 0.074] | 0.018* |
APOE ε2 allele | 0.63 [0.18, 1.07] | 0.006* |
APOE ε4 allele | − 0.12 [− 0.36, 0. 13] | 0.34 |
*p < 0.05.