Table 5.
Regression coefficients demonstrating the associations between tau deposition on [18F]-flortaucipir PET and neutrophil-to-lymphocyte and lymphocyte-to-monocyte ratios.
| Regression coefficient [95% CI] | p-value | |
|---|---|---|
| Neutrophil-to-Lymphocyte Ratio | ||
| Regional tau PET SUVR in meta-temporal regions | − 0.060 [− 0.23, 0.11] | 0.50 |
| Regional tau PET SUVR in Braak 1 regions | − 0.042 [− 0.23, 0.15] | 0.66 |
| Regional tau PET SUVR in Braak 3 and 4 regions | − 0.040 [− 0.16, 0.085] | 0.53 |
| Regional tau PET SUVR in Braak 5 and 6 regions | − 0.022 [− 0.10, 0.055] | 0.57 |
| Regional tau PET SUVP in the medial temporal regions | − 0.015 [− 0.100, 0.071] | 0.73 |
| Lymphocyte-to-Monocyte ratio | ||
| Regional tau PET SUVR in meta-temporal regions | − 0.018 [− 0.15, 0.12] | 0.80 |
| Regional tau PET SUVR in Braak 1 regions | − 0.049 [− 0.20, 0.097] | 0.51 |
| Regional tau PET SUVR in Braak 3 and 4 regions | − 0.014 [− 0.11, 0.083] | 0.77 |
| Regional tau PET SUVR in Braak 5 and 6 regions | − 0.027 [− 0.087, 0.034] | 0.38 |
| Regional tau PET SUVP in the medial temporal regions | − 0.0030 [− 0.065, 0.059] | 0.92 |
SUVR standardized uptake value ratio.
SUVP standardized uptake value peak alignment.
Values shown are regression coefficients [95% CI] (p-values). Regression models included age, sex, years of education, cognitive status, and APOE genotype as covariates.