Figure 7.

Ensemble of endosomes is heterogeneous as revealed by the dependence of the generalized diffusion coefficients on the trajectories duration. (a,b) Conditional eMSDs (eMSD calculated for the subsets of trajectories with a duration longer than T seconds) as functions of time t in MRC5 and RPE cells, respectively. Trajectories longer than 8 s (curves $T>8$ s and $T>15$ s) become diffusive at longer times. The dotted lines are linear functions to guide the eyes. (c) The numerical value of the conditional generalized diffusion coefficient, $D_{\alpha }(t|T)$, extracted from eMSDs in (a,b) by fitting to Eq. (6) , as a function of the minimal duration of trajectories T. The dashed and dashed-dotted lines correspond to power law functions $T^{-\gamma }$ with exponents $\gamma$ given in the figure. Notice that the units of the generalized diffusion coefficient are $[\mathrm{\mu }{\text{m}}^2/{\text{s}}^{\alpha }]$.