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. 2023 May 31;9:82. doi: 10.1038/s41531-023-00527-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Heat map visualization of 921 differentially expressed genes (DEGs) between PD and control nigrostriatal (SN) RNA. b The weighted gene co-expression network analysis (WGCNA) was performed with the DEGs expression data to identify the Braak stage related models. c Volcano map visualization of 1001 DEGs between PD and control blood samples of GSE99039. d, e Venn diagrams and scatter plots show the distribution of the overlapping 58 genes.