HUVECs Migration after 1 day of incubation with different culture mediums or leachates. (A) HUVECs monolayer was scratched using a tip of a 100 μl pipette. The position of the initial scratch edge is illustrated with dotted lines, at the beginning of the experiment and after a day of incubation with different culture mediums or leachates. (B) The ratio (%) of cell-coverd area was evaluated after 1 day compared to the initial gap between scratch borders. (C) Quantification of secreted VEGF from HUVEC for different groups on day 5. Note: scale bars 200 μm. Data presented as mean ± SD, n = 3, all statistical significance shown in comparison to control group unless otherwise stated, ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.