TABLE 1.
Characteristics of patients prescribed aspirin in the T1DM patient group.
| Characteristic | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
| Aspirin cohort | Non-aspirin cohort | SMD | Aspirin cohort | Non-aspirin cohort | SMD | |
| Total no. | 14,376 | 24,180 | 9,608 | 9,608 | ||
| Age | 63.6 ± 12.2 | 60.4 ± 13.6 | 0.24* | 62.5 ± 12.2 | 62.3 ± 12.4 | 0.02 |
| Sex assigned at birth, % | ||||||
| Female | 53.1 | 55.4 | 0.04 | 52.9 | 52.7 | 0.004 |
| Male | 46.8 | 44.5 | 0.04 | 47.1 | 47.2 | 0.004 |
| Ethnicity, % | ||||||
| Hispanic/Latinx | 11.6 | 11.9 | 0.008 | 12.1 | 12.1 | 0.005 |
| Non-Hispanic/Latinx | 66.3 | 53.9 | 0.25* | 63.5 | 64.6 | 0.02 |
| Race, % | ||||||
| African/ U.S. citizens/Black | 25.4 | 19.3 | 0.14* | 23.5 | 24.1 | 0.01 |
| White | 60.1 | 57.1 | 0.06 | 60.4 | 61.7 | 0.02 |
| Asian | 1.5 | 1.4 | 0.001 | 1.5 | 1.3 | 0.01 |
| Comorbidities, % | ||||||
| Hypertension | 90.3 | 76.1 | 0.39* | 88.5 | 89.1 | 0.01 |
| Tobacco use | 4.8 | 3.9 | 0.04 | 4.8 | 4.5 | 0.01 |
| Glaucoma | 26.7 | 11.7 | 0.38* | 19.4 | 19.2 | 0.006 |
| Dry eye syndrome | 17.5 | 5.9 | 0.36* | 10.7 | 10.4 | 0.01 |
| Degeneration of macula and posterior pole | 17.1 | 5.5 | 0.36* | 10.1 | 9.2 | 0.02 |
| Other drugs, % | ||||||
| Drugs used in DM | 80.4 | 59.6 | 0.46* | 77.1 | 77.3 | 0.008 |
Note: SMD, standardized mean differences. *SMD, greater than 0.1, is a recommended threshold for declaring an imbalance.