Table 2.
Functions of ncRNAs in resistance of silkworm to disease and viral replication.
| Name | Author | Type | Experimental tissue (cell) | Expression level | Description |
|---|---|---|---|---|---|
| Bmo-miR-282 | Jiang (2019) | miRNA | Strain P50 | Upregulated in infected strain P50 larvae | The expression level was changed by infection, which was related to virus replication |
| Bmo-miR-10-5p | Jiang (2019) | miRNA | Strain P50 | Upregulated in infected strain P50 larvae | Related to the replication of virus |
| Bmo-miR-277-5p | Jiang (2019) | miRNA | Strain P50 | Upregulated in infected silkworm P50 larvae | Experiments showed this miRNA can interact with Dnmt2 which could cause several immune pathways |
| Bmo-miR-3378 | Jiang (2019) | miRNA | BmN cell | The overexpressing of Bmo-miR-3378 significantly reduced the viral amount | |
| Bmo-miR-390 | Kang et al. (2018) | miRNA | Hemolymph | The expression was significantly reduced after virus infection | Expression changed with the increase of time after infection and showed the ability to downregulate the cg30 in vitro |
| Bmo-miR-217 | Wang M. L. et al. (2017) | miRNA | Hemolymph | The experimental group was higher than that in the treatment group after infected | Interacting with lef-1 which could inhibit the lef-1 |
| Bmo-miR-2819 | Wu et al. (2019a) | miRNA | BmN cell | Expression decreased after viral infection in BmN cells | After infection of the virus, the expression of miR-2819 would inhibit virus |
| Bmnpv-miR-1 | Singh et al. (2012) | miRNA | BmNPV | – | Bmnpv-miR-1 indirectly caused decrease in the host own miRNA, which will promote viral replication |
| Bmnpv-miR-3 | Singh et al. (2014) | miRNA | BmNPV | – | By regulating P6.9 protein and various viral proteins which could promote virus replication |
| BmNPV-miR-415 | Cao et al. (2017) | miRNA | BmNPV | – | Viral miRNA induced host Bmo-miR-5738 to regulate TOR2, and thus regulated viral replication |
| KO122AS | Ishihara et al. (2015) | lncRNA | BmNPV | – | Mutants of KO122AS could produce fewer OB virions than wild type |
| Lnc_209997 | Lin et al. (2022) | lncRNA | Fat body | The expression of BmNPV was significantly down-regulated after infection | By regulating miR-275-5p to promote the replication of virus |
| circEgg | Wang et al. (2020) | circRNA | Strain DaZao | – | Through bmo-miR-3391 to regulate the acetylase expression |