TABLE 5.
Effect of different concentrations of PSPL extracts on blood biochemistry analysis of diabetic rats during the 12-week treatment phase. The different letter indicates a significant difference at p < 0.05 among the tested groups. Values are expressed as mean ± SEM.
| NS | DNS | DT 200 | DT 400 | D25G | |
|---|---|---|---|---|---|
| Renal function test | |||||
| Sodium (mmol/L) | 147.50 ± 0.56a | 141.17 ± 1.08b | 140.60 ± 1.17b | 142.67 ± 0.76a | 140.00 ± 3.42b |
| Potassium (mmol/L) | 7.77 ± 0.45 | 9.23 ± 0.46 | 8.80 ± 0.37 | 7.98 ± 0.15 | 8.46 ± 0.48 |
| Chloride (mmol/L) | 100.83 ± 0.70a | 92.83 ± 1.58a | 95.80 ± 3.07a | 92.33 ± 0.61b | 91.25 ± 4.03b |
| Urea (mmol/L) | 6.57 ± 0.52 | 5.58 ± 0.90 | 8.43 ± 1.32 | 8.20 ± 0.32 | 6.04 ± 1.26 |
| Creatinine (mmol/L) | 50.00 ± 3.60 | 58.67 ± 3.91 | 52.75 ± 2.95 | 59.50 ± 2.27 | 58.20 ± 3.01 |
| Liver function test | |||||
| Total protein (g/L) | 66.83 ± 2.09 | 68.33 ± 2.74 | 63.80 ± 1.83 | 68.17 ± 2.01 | 64.60 ± 3.50 |
| Albumin (g/L) | 38.67 ± 1.37 | 39.33 ± 1.38 | 35.40 ± 0.68 | 37.00 ± 0.69 | 36.00 ± 1.48 |
| Globulin (g/L) | 28.17 ± 0.86 | 29.00 ± 1.65 | 28.40 ± 1.36 | 31.17 ± 1.53 | 28.60 ± 2.64 |
| Albumin–globulin ratio | 1.37 ± 0.03 | 1.36 ± 0.06 | 1.26 ± 0.06 | 1.21 ± 0.04 | 1.29 ± 0.10 |
| ALP (U/L) | 108.17 ± 13.84a | 701.75 ± 147.17b | 336.00 ± 69.06a | 163.00 ± 17.09a | 899.75 ± 223.26b |
| AST (U/L) | 120.80 ± 5.63 | 89.33 ± 10.70 | 132.20 ± 21.09 | 131.83 ± 21.10 | 249.20 ± 92.64 |
| ALT (U/L) | 77.00 ± 8.50 | 139.00 ± 21.65 | 128.00 ± 22.21 | 114.50 ± 24.08 | 313.80 ± 159.39 |
| Gamma-glutamyl transferase (U/L) | 2.67 ± 0.56 | 2.67 ± 0.33 | 4.25 ± 0.22 | 4.00 ± 1.15 | 3.60 ± 0.40 |