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. 2023 May 18;14:1163811. doi: 10.3389/fneur.2023.1163811

Figure 2.

Figure 2

Motor outcomes and recordings in resting state, via the Brainsense™ Streaming, of the STN-LFP in different conditions. (A) Motor outcomes (MDS-UPDRS III, alternate index finger tapping test, and TUGT scores) in the four conditions (MED-OFF/STIM-ON, MED-OFF/STIM-OFF, MED-ON/STIM-OFF, and MED-ON/STIM-ON). (B) Recordings in the resting state of the LFP in the right STN recorded via the Brainsense™ Streaming in different conditions. In the mid part of the graph: Spectrograms extracted from the raw LFP. In the lower part of the graph: the relative spectral power of the raw LFP in the frequency range 0–80 Hz. Blue and red arrows highlight the identified peaks in the low−/high-beta frequency band, respectively. In the upper part of the graph: relative spectral power of the peaks in the low-beta and high-beta frequency bands plotted over time, together with the L-dopa concentration. (C) Recordings in the resting state of the LFP in the left STN recorded via the Brainsense™ Streaming in different conditions. In the mid part of the graph: Spectrograms extracted from the raw LFP. In the lower part of the graph: the relative spectral power of the raw LFP in the frequency range 0–80 Hz. Blue and red arrows highlight the identified peaks in the low−/high-beta frequency band, respectively. In the upper part of the graph: relative spectral power of the peaks in the low-beta and high-beta frequency bands plotted over time, together with the L-dopa concentration. L-dopa, levodopa; MDS-UPDRS, Movement Disorder Society-Unified Parkinson’s Disease Rating Scale part III, motor subsection; MED-OFF, OFF medications; MED-ON, ON medications; STIM-OFF, OFF stimulation; STIM-ON, ON stimulation; TUGT, timed up and go test.