Table 2.
Microbiology finding of culture, mNGS and tNGS in all cases.
| Microorganism | Culture (n) | mNGS (n) | tNGS (n) |
|---|---|---|---|
| Staphylococcus aureus | 15 | 14 | 17 |
| CoNS a | 6 | 11 | 10 |
| Streptococcus b | 7 | 8 | 8 |
| Gram-negative bacillic | 3 | 4 | 3 |
| Pseudomonas d | 3 | 1 | 4 |
| Enterococcus faecalis | 0 | 1 | 0 |
| Salmonella | 2 | 1 | 2 |
| Candida e | 1 | 2 | 2 |
| Mycoplasma hominis | 0 | 1 | 1 |
| Other organismsf | 0 | 4 | 3 |
| Total | 37 | 47 | 45 |
mNGS, metagenomic next-generation sequencing; tNGS, targeted next-generation sequencing.
a
Coagulase negative staphylococcus.
b
Including Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus gallolyticus, Streptococcus anginosus, Streptococcus spp.
c
Including Escherichia coli, Stenotrophomonas maltophilia, Enterobacter hormaechei, Afipia broomeae.
d
Including Pseudomonas alcaligenes, Pseudomonas aeruginosa, Pseudomonas monteilii, Pseudomonas spp.
e
Including Candida albicans, Candida parapsilosis.
f
Including Corynebacterium striatum, Cutibacterium acnes, Finegoldia magna, Enterococcus casseliflavus, Neisseria spp.