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. 2023 May 18;14:1166680. doi: 10.3389/fimmu.2023.1166680

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Copyright © 2023 Li, Fu, Cheng, Elfiky, Wei and Fu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heat shock protein A5 (HSPA5) expression comparisons in cancers and paired normal samples and its comparison among different entry proteins in pan-cancers. (A) HSPA5 expression in cancers and paired normal samples in 33 types of cancers. (B) Expression comparisons among HSPA5, angiotensin-converting enzyme 2 (ACE2), cathepsin L (CTSL), transmembrane protease serine 2 (TMPRSS2), transmembrane protease serine 4 (TMPRSS4), ADAM metallopeptidase domain 17 (ADAM17), neuropilin-1 (NRP1), and dipeptidyl peptidase-4 (DPP4) in both malignant cancers and corresponding normal samples in 31 types of cancers in The Cancer Genome Atlas (TCGA) datasets. The expression analysis was conducted in Gene Expression Profiling Interactive Analysis (GEPIA2) (http://gepia2.cancer-pku.cn/#analysis). “T” stands for tumor tissue, and “N” stands for the matched normal tissue.