TABLE 3.
Top 10 enriched significant GO terms of different ontologies for target genes of miR-155-5p.
| Ontology | GO id | Description | p-value | Gene number |
|---|---|---|---|---|
| Biological process | 0031326 | regulation of cellular biosynthetic process | 3.77E-06 | 37 |
| 0009889 | regulation of biosynthetic process | 5.29E-06 | 37 | |
| 0019219 | regulation of nucleobase-containing compound metabolic process | 2.04E-05 | 35 | |
| 2000112 | regulation of cellular macromolecule biosynthetic process | 2.36E-05 | 34 | |
| 0006730 | one-carbon metabolic process | 2.40E-05 | 4 | |
| 0010556 | regulation of macromolecule biosynthetic process | 2.84E-05 | 34 | |
| 0006355 | regulation of transcription, DNA-templated | 4.07E-05 | 31 | |
| 1903506 | regulation of nucleic acid-templated transcription | 4.11E-05 | 31 | |
| 2001141 | regulation of RNA biosynthetic process | 4.35E-05 | 31 | |
| 0034654 | nucleobase-containing compound biosynthetic process | 4.45E-05 | 35 | |
| Cellular component | 0043231 | intracellular membrane-bounded organelle | 5.35E-03 | 58 |
| 0090575 | RNA polymerase II transcription factor complex | 6.28E-03 | 4 | |
| 0043227 | membrane-bounded organelle | 6.99E-03 | 63 | |
| 0036488 | CHOP-C/EBP complex | 8.27E-03 | 1 | |
| 1990617 | CHOP-ATF4 complex | 8.27E-03 | 1 | |
| 1990622 | CHOP-ATF3 complex | 8.27E-03 | 1 | |
| 0044798 | nuclear transcription factor complex | 8.47E-03 | 4 | |
| 0098636 | protein complex involved in cell adhesion | 1.03E-02 | 2 | |
| 0005634 | nucleus | 1.05E-02 | 42 | |
| 0008247 | 1-alkyl-2-acetylglycerophosphocholine esterase complex | 1.24E-02 | 1 | |
| Molecular function | 0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 1.16E-05 | 18 |
| 0003700 | DNA-binding transcription factor activity | 2.04E-05 | 18 | |
| 0004222 | metalloendopeptidase activity | 8.71E-05 | 5 | |
| 0004694 | eukaryotic translation initiation factor 2alpha kinase activity | 1.06E-04 | 2 | |
| 0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | 1.10E-04 | 9 | |
| 0140110 | transcription regulator activity | 1.35E-04 | 20 | |
| 0043565 | sequence-specific DNA binding | 1.64E-04 | 18 | |
| 0008237 | metallopeptidase activity | 1.64E-04 | 6 | |
| 0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2.19E-04 | 16 | |
| 0001012 | RNA polymerase II regulatory region DNA binding | 2.19E-04 | 16 |