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Treatment related adverse events.
| Toxicity | All grades n (%) | G3-4 n (%) |
|---|---|---|
| Fatigue | 9 (21%) | 2 (5%) |
| Skin reactions (including HFS) | 6 (14%) | 2 (5%) |
| Diarrhea | 6 (14%) | 1 (2%) |
| Hypertension | 5 (12%) | 2 (5%) |
| Proteinuria | 4 (10%) | 3 (7%) |
| Rheumatologic toxicity | 3 (7%) | 1 (2%) |
| Elevated LFTs | 2 (5%) | 0 (0%) |
| Anemia | 1 (2%) | 1 (2%) |
| Perforation | 1 (2%) | 1 (2%) |
G3-4, Grade 3-4; LFTs, liver function tests; HFS, hand & foot syndrome.
