AFP |
alpha-fetoprotein |
ACT |
Adoptive Cell Therapy |
α-SMC |
α-smooth muscle cell |
CAR |
chimeric antigen receptor |
CCL26 |
C-C motif chemokine 26 |
CIK |
cytokine-induced killing |
CTLA-4 |
cytotoxic T lymphocyte associated protein 4 |
CAF |
cancer-associated fibroblasts |
CTL |
cytotoxic T lymphocyte |
CSC |
sequester circulating cancer cells |
CCA |
cholangiocarcinoma |
CXCL |
chemokine (C-X-C motif) ligand |
CYLD |
cylindromatosis |
CVV |
cancer-favoring vaccinia virus |
cDCs |
conventional DCs |
DC |
dendritic cells |
DCR |
disease control rate |
ECM |
extracellular matrix |
EMT |
epithelial–mesenchymal transition |
FDA |
US Food and Drug Administration |
FoxP3 |
forkhead box protein 3 |
FGF |
fibroblast growth factor |
FAP |
fibroblast activating protein |
GPC3 |
Glypican 3 |
GM-CSF |
granulocyte-macrophage colony stimulating factor |
HCC |
Hepatocellular carcinoma |
HSC |
hepatic stellate cell |
hTERT |
telomerase reverse transcriptase |
ICB |
immune checkpoint blockade |
ICIs |
immune checkpoint inhibitors |
IDO |
indoleamine-2,3-dioxygenase |
IFN-γ |
interferon gamma |
KCs |
Kupffer cells |
KIT |
c-kit receptor |
LPS |
lipopolysaccharide |
LSAMP |
limbic system-associated membrane protein |
LAG-3 |
lymphocyte-activation gene 3 |
MDSC |
myeloid-derived suppressor cells |
MC |
mast cells |
MST |
median survival time |
MFB |
myofibroblast |
MHC |
major histocompatibility complex |
NK |
natural killer cells |
NET |
neutrophil extracellular traps |
NKG2D |
natural killer group 2D |
NKG2A |
natural killer group 2A |
NGF |
nerve growth factor |
NY-ESO-1 |
New York esophageal squamous cell carcinoma 1 |
NMPA |
national medical products administration |
OS |
overall survival |
OVs |
oncolytic viruses |
ORR |
objective remission rates |
OS |
overall survival |
PD1 |
programmed cell death 1 |
PD-L1 |
programmed death ligand 1 |
PFS |
progression-free survival |
PBMC |
peripheral blood mononuclear cells |
PDGF |
platelet-derived growth factor |
PDGFR |
platelet-derived growth factor receptor |
pDCs |
plasma cell-like DCs |
RFA |
radiofrequency ablation |
RFS |
recurrence-free survival |
SIRT |
selective internal radiation therapy |
SBRT |
stereotactic body radiation therapy |
TAA |
tumor-associated antigen |
TACE |
transarterial chemoembolization |
TIL |
tumor infiltrating lymphocytes |
TAM |
tumor-associated macrophages |
TAN |
tumor-associated neutrophils |
TGF-β |
transforming growth factor-β |
TNF-α |
tumor necrosis factor-α |
TCR |
T cell receptor |
TIGIT |
T cell immune receptor with Ig and ITIM domains |
Tim-3 |
T cell immunoglobulin and mucin domain-containing protein 3 |
VEGF |
vascular endothelial growth factor |
VEGFR |
vascular endothelial growth factor receptor. |