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. 2023 May 18;14:1188277. doi: 10.3389/fimmu.2023.1188277
AFP alpha-fetoprotein
ACT Adoptive Cell Therapy
α-SMC α-smooth muscle cell
CAR chimeric antigen receptor
CCL26 C-C motif chemokine 26
CIK cytokine-induced killing
CTLA-4 cytotoxic T lymphocyte associated protein 4
CAF cancer-associated fibroblasts
CTL cytotoxic T lymphocyte
CSC sequester circulating cancer cells
CCA cholangiocarcinoma
CXCL chemokine (C-X-C motif) ligand
CYLD cylindromatosis
CVV cancer-favoring vaccinia virus
cDCs conventional DCs
DC dendritic cells
DCR disease control rate
ECM extracellular matrix
EMT epithelial–mesenchymal transition
FDA US Food and Drug Administration
FoxP3 forkhead box protein 3
FGF fibroblast growth factor
FAP fibroblast activating protein
GPC3 Glypican 3
GM-CSF granulocyte-macrophage colony stimulating factor
HCC Hepatocellular carcinoma
HSC hepatic stellate cell
hTERT telomerase reverse transcriptase
ICB immune checkpoint blockade
ICIs immune checkpoint inhibitors
IDO indoleamine-2,3-dioxygenase
IFN-γ interferon gamma
KCs Kupffer cells
KIT c-kit receptor
LPS lipopolysaccharide
LSAMP limbic system-associated membrane protein
LAG-3 lymphocyte-activation gene 3
MDSC myeloid-derived suppressor cells
MC mast cells
MST median survival time
MFB myofibroblast
MHC major histocompatibility complex
NK natural killer cells
NET neutrophil extracellular traps
NKG2D natural killer group 2D
NKG2A natural killer group 2A
NGF nerve growth factor
NY-ESO-1 New York esophageal squamous cell carcinoma 1
NMPA national medical products administration
OS overall survival
OVs oncolytic viruses
ORR objective remission rates
OS overall survival
PD1 programmed cell death 1
PD-L1 programmed death ligand 1
PFS progression-free survival
PBMC peripheral blood mononuclear cells
PDGF platelet-derived growth factor
PDGFR platelet-derived growth factor receptor
pDCs plasma cell-like DCs
RFA radiofrequency ablation
RFS recurrence-free survival
SIRT selective internal radiation therapy
SBRT stereotactic body radiation therapy
TAA tumor-associated antigen
TACE transarterial chemoembolization
TIL tumor infiltrating lymphocytes
TAM tumor-associated macrophages
TAN tumor-associated neutrophils
TGF-β transforming growth factor-β
TNF-α tumor necrosis factor-α
TCR T cell receptor
TIGIT T cell immune receptor with Ig and ITIM domains
Tim-3 T cell immunoglobulin and mucin domain-containing protein 3
VEGF vascular endothelial growth factor
VEGFR vascular endothelial growth factor receptor.