Table 1.
Baseline characteristics of dogs in the two treatment groups in the trial population.
| Treatment groups | |||
|---|---|---|---|
| Characteristic | Rapamycin (n = 9) | Placebo (n = 8) | |
| Age at enrollment (years) | 7.8 (1.0) | 8.5 (1.7) | |
| Sex and castration status | Male/castrated | 4 (44.4) | 2 (25.0) |
| Female/spayed | 4 (44.4) | 6 (75.0) | |
| Female/intact | 1 (11.1) | 0 (0.0) | |
| Breed category | Herding | 2 (22.2) | 4 (50.0) |
| Sporting | 4 (44.4) | 2 (25.0) | |
| Terrier | 1 (11.1) | 0 (0.0) | |
| Working | 2 (22.2) | 0 (0.0) | |
| Other | 0 (0.0) | 2 (25.0) | |
| Body condition score | 4 | 3 (33.3) | 0 (0.0) |
| 5 | 4 (44.4) | 4 (50.0) | |
| 6 | 2 (22.2) | 4 (50.0) | |
| Left atrial to aortic root ratio | 1.16 (0.12) | 1.19 (0.17) | |
| Ejection fraction (%) | 58.3 (11.3) | 58.6 (8.1) | |
| Fractional shortening (%) | 30.1 (9.7) | 32.2 (8.5) | |
| E to A wave ratio | 1.15 (0.30) | 0.98 (0.27) | |
Continuous variables are reported as mean (standard deviation). Categorical variables are reported as number (%).