Table 3.

Diastolic functional class of the rapamycin and placebo groups at baseline, 6 months, and 12 months into the study.

Treatment group	Diastolic functional class*	Baseline	6 months	12 months
Rapamycin	Class 1	4 (44.4)	4 (44.4)	6 (66.7)
	Class 2	3 (33.3)	4 (44.4)	0 (0.0)
	Class 3	2 (22.2)	0 (0.0)	3 (33.3)
	Class 4	0 (0.0)	0 (0.0)	0 (0.0)
Placebo	Class 1	0 (0.0)	2 (25.0)	2 (25.0)
	Class 2	4 (50.0)	2 (25.0)	4 (50.0)
	Class 3	4 (50.0)	4 (50.0)	2 (25.0)
	Class 4	0 (0.0)	0 (0.0)	0 (0.0)

Categorical variables reported as number (%). *Diastolic functional classes are defined as normal pattern (Class 1), relaxation delay pattern (Class 2), pseudonormal pattern (Class 3), and restrictive pattern (Class 4) (55).