Table 2.

Formulas for the calculation of the treatment frequency.

Definition	Formula
Sum of animal days	Animal days $=Day{s}_{Animal1}$ + $Day{s}_{Animal2}$ + $Day{s}_{Animal3}+$ ... + $Day{s}_{Animaln}$
Average number of animals kept	Average number $=\frac{Animal\mathrm{}days}{Days\mathrm{}ofahalf\mathrm{}year}$
Treatment frequency	$Treatment\mathrm{}frequency=\frac{Number\mathrm{}of\mathrm{}treated\mathrm{}animals.Days\mathrm{}under\mathrm{}treatment.Number\mathrm{}of\mathrm{}active\mathrm{}ingredients}{Average\mathrm{}number\mathrm{}of\mathrm{}animals\mathrm{}kept}$