Table I.

Number of chromosomal abnormality and congenital malformation diagnoses among 5011 women with premature ovarian insufficiency (POI) reported in the Hospital Discharge Register during the follow-up period.

	n	%
Genetic disorders
Turner syndrome	256	5.13
Autosome chromosomal abnormalities	35	0.70
Sex chromosome abnormalities*	44	0.88
Autosomal single-gene disorders	28	0.56
Other chromosomal abnormalities	5	0.10
Congenital malformations of gynaecological organs
Congenital malformations of the ovary, fallopian tubes and broad ligaments	101	2.02
Congenital malformations of the uterus and cervix	47	0.94
Other congenital malformations of female genitalia	19	0.38
Other congenital malformations
Skin and mammary gland anomalies	57	1.14
Congenital malformations of the nervous system	31	0.62
Congenital malformations of the eye, ear, face, and neck	84	1.68
Congenital malformations of the circulatory system	120	2.41
Cleft lip and cleft palate	20	0.40
Other congenital malformations of the digestive system	47	0.94
Congenital malformations of the urinary system	42	0.84
Congenital malformations and deformations of the musculoskeletal system	197	3.95
Unspecified congenital malformations	45	0.90
Disorder of sexual differentiation/development	7	0.1
Congenital malformations of the respiratory system	9	0.2
Congenital malformation syndromes due to known exogenous causes	1–4	<0.1
Congenital malformations of spleen or endocrine glands	1–4	<0.1

^*Turner syndrome excluded.