Figure 1.

Distribution of plasma p-tau₁₈₁ concentrations between brain donors with and without autopsy-confirmed Alzheimer’s disease. NIA–Reagan Institute criteria were used for the neuropathological diagnosis of Alzheimer’s disease. Analyses were done in the entire sample (n = 62 Alzheimer’s disease versus 41 non-Alzheimer’s disease) and stratified by CDR score ≥1 (n = 37 Alzheimer’s disease versus n = 9 non-Alzheimer’s disease) and CDR score <1 (n = 25 Alzheimer’s disease versus n = 32 non-Alzheimer’s disease). Figure shows the median (bar) and interquartile range (whiskers) as well as the individual data points. Results of the binary logistic regression models that tested the association between plasma p-tau₁₈₁ and Alzheimer’s disease status in the entire sample and stratified by CDR are shown in Table 3. p-tau = phosphorylated-tau.