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. 2022 May 23;145(10):3608–3621. doi: 10.1093/brain/awac188

Figure 1.

Figure 1

Behaviour in PtenT366A/T366A mice. (A) PtenT366A/T366A and wild-type (wt) siblings tested for general exploratory behaviour in the open field. (B and C) Motor skills as determined in the hanging wire test (B) and in the rotarod (C). (D) Percentage of total responses to mechanical stimulation in the von Frey test in PtenT366A/T366A and wild-type siblings. (E) Percentage of spontaneous alterations in the Y-maze in female and in male PtenT366A/T366A and wild-type siblings. (F) Percentage of time that PtenT366A/T366A and wild-type mice spent in the target area and other quadrants of the Barnes maze. (G) Percentage of time that PtenT366A/T366A and wild-type mice spent in the target area and other quadrants of the Morris water maze. (H) Percentage freezing in the conditioned fear-induced freezing in female and in male PtenT366A/T366A and wild-type siblings. (I) The average number of responses in the vibrissae-stimulated reflex test of PtenT366A/T366A and wild-type siblings. (K) Grooming time in PtenT366A/T366A and wild-type mice. Statistical analysis with one-way ANOVA (Bonferroni post hoc test), unpaired t-test, Wilcoxon test (grooming), *P < 0.05. For analysis details see Supplementary Table 3.