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. 2023 Jun 1;13(24):16413–16452. doi: 10.1039/d3ra01888a

Chemical structures of hydrazones derivatives and IC50 values against AP inhibitors.

Compound no. Chemical structures & IUPAC names IC50 (μM) References
h-TNAP h-IAP h-PLAP h-GCAP
16 graphic file with name d3ra01888a-u7.jpg 43.8% 42.8% 44.8% 0.74 133
17 graphic file with name d3ra01888a-u8.jpg 42.1% 0.32 0.048 36.7% 133
18 graphic file with name d3ra01888a-u9.jpg 0.13 0.01 0.059 45.7% 133
19 graphic file with name d3ra01888a-u10.jpg 0.026 47.2% 5.04 33.5% 133
Standards graphic file with name d3ra01888a-u11.jpg 25 120 133
graphic file with name d3ra01888a-u12.jpg 100 300 133