. 2023 Jun 1;13(24):16413–16452. doi: 10.1039/d3ra01888a

Chemical structures of quinoline-4-carboxylic acid derivatives and IC₅₀ values against AP inhibitors.

Compound no.	Chemical structures & IUPAC names	IC₅₀ (μM)				References
Compound no.	Chemical structures & IUPAC names	h-TNAP	h-IAP	h-PLAP	h-GCAP	References
21		0.36	0.03	0.08	29	135
22		0.02	0.27	0.65	48	135
23		0.42	0.07	0.32	0.15	135
Standards		28.2	—	120	—	135
Standards		—	100	—	301	135

Chemical structures of quinoline-4-carboxylic acid derivatives and IC50 values against AP inhibitors.