. 2023 Jun 1;13(24):16413–16452. doi: 10.1039/d3ra01888a

Chemical structures of isonicotinohydrazide derivatives and IC₅₀ values against AP inhibitors.

Compound no.	Chemical structures & IUPAC names	IC₅₀ (μM)				References
Compound no.	Chemical structures & IUPAC names	h-e5′NT	r-e5′NT	b-TNAP	c-IAP	References
46		0.19	0.36	1.06	3.98	143
47		0.68	0.14	0.35	1.92	143
48		1.67	1.08	48.95%	0.67	143
Standards		—	—	19.2	—	143
		—	—	—	80.2	143
		42.1	77.3	—	—	143

Chemical structures of isonicotinohydrazide derivatives and IC50 values against AP inhibitors.