Table 4.
Differential expression results highlighting various genes associated with competence and virulence being upregulated when comparing DMSO (negative control) to synthetic CSP
|
Locus tag |
Gene |
Annotation |
Log2 change |
P-adj |
|---|---|---|---|---|
|
FOA32_000391 |
comYA |
Competence protein YA |
1.1362 |
1.96E-05 |
|
FOA32_000390 |
comYB |
Competence protein YB |
1.4176 |
7.27E-08 |
|
FOA32_000389 |
comYC |
Competence protein YC |
1.3002 |
1.21E-05 |
|
FOA32_000388 |
comYD |
Competence protein YD |
0.6785 |
2.42E-02 |
|
FOA32_000386 |
comGF |
Competence protein GF |
1.1461 |
2.46E-06 |
|
FOA32_000664 |
celA |
Competence protein |
1.4683 |
1.05E-03 |
|
FOA32_000665 |
comEC |
Competence protein |
1.8266 |
3.21E-15 |
|
FOA32_000685 |
coiA |
Competence protein |
0.8556 |
2.51E-03 |
|
FOA32_001444 |
comA |
ABC transporter |
1.1788 |
1.51E-06 |
|
FOA32_001445 |
comB |
ABC transporter |
0.8518 |
3.91E-04 |
|
FOA32_000049 |
comX |
Transcriptional regulator of competence-specific genes |
1.8639 |
5.05E-11 |
|
FOA32_001005 |
cinA |
Competence–damage inducible protein A |
1.9992 |
1.53E-18 |
|
FOA32_001482 |
comC |
Competence-stimulating peptide |
1.4634 |
1.08E-07 |
|
FOA32_001481 |
comD |
Histidine kinase |
0.8049 |
3.67E-03 |
|
FOA32_001480 |
comE |
Response regulator |
0.9189 |
4.93E-04 |
|
FOA32_001238 |
recX |
Recombination protein |
1.8172 |
2.60E-14 |
|
FOA32_001890 |
rmuC |
Recombination protein |
1.3208 |
6.69E-08 |
|
FOA32_000639 |
recN |
DNA repair protein |
1.0128 |
6.99E-03 |
|
FOA32_000971 |
cap3 |
UDP-glucose-6-dehyrogenase |
0.6498 |
1.74E-03 |
|
FOA32_001484 |
htrA |
Serine protease |
0.5213 |
4.87E-02 |
|
FOA32_001961 |
pbp 2A |
enicillin-binding protein 2A |
0.9618 |
8.45E-06 |