Table 5.
Differential expression results highlighting various genes associated with competence and virulence being downregulated when comparing DMSO (negative control) to synthetic CSP
|
Locus tag |
Gene |
Annotation |
log2 FC |
p-adj |
|---|---|---|---|---|
|
FOA32_000227 |
ccpA |
Catabolite control protein A |
−0.7463 |
6.89E-03 |
|
FOA32_001808 |
- |
PTS fructose transporter subunit IIA |
−0.9372 |
1.16E-04 |
|
FOA32_001809 |
- |
PTS fructose transporter subunit IID |
−0.9665 |
8.87E-05 |
|
FOA32_000099 |
- |
PTS glucose transporter subunit IIABC |
−0.6123 |
3.76E-02 |
|
FOA32_001341 |
- |
PTS mannose/fructose/sorbose transporter subunit IIC |
−1.1371 |
4.67E-06 |
|
FOA32_000475 |
crcB |
Putative fluoride ion transporter |
−0.8183 |
2.49E-02 |
|
FOA32_000035 |
mecA |
Adapter protein |
−0.8028 |
1.49E-02 |
|
FOA32_000761 |
amy |
Alpha-amylase |
−1.2753 |
4.96E-04 |
|
FOA32_001226 |
ftsA |
Cell division protein |
−0.6769 |
2.98E-02 |
|
FOA32_000717 |
ftsX |
Cell division protein |
−0.9199 |
1.40E-02 |
|
FOA32_001028 |
malR |
LacI family transcriptional regulator |
−0.6059 |
4.17E-02 |
|
FOA32_000006 |
rsfS |
Ribosomal silencing factor |
−1.4111 |
4.93E-04 |
|
FOA32_001645 |
tig |
Trigger factor |
−0.6221 |
4.44E-02 |
|
FOA32_001049 |
- |
Type VII secretion protein EssA |
−0.9494 |
1.12E-02 |
|
FOA32_001443 |
rpsD |
30S ribosomal protein S4 |
−1.2171 |
7.21E-08 |
|
FOA32_001630 |
rpsH |
30S ribosomal protein S8 |
−0.9610 |
2.05E-03 |
|
FOA32_001505 |
rplM |
50S ribosomal protein L13 |
−1.2907 |
6.32E-05 |
|
FOA32_001635 |
rplO |
50S ribosomal protein L15 |
−1.0335 |
7.64E-04 |
|
FOA32_000259 |
infC |
Translation initiation factor |
−1.1224 |
8.05E-06 |
|
FOA32_000143 |
- |
Membrane protein |
−0.9259 |
1.34E-02 |
|
FOA32_000586 |
- |
Membrane protein |
−0.8700 |
1.59E-02 |
|
FOA32_000860 |
scrB |
Membrane protein |
−0.6828 |
1.84E-02 |
|
FOA32_001191 |
yidC_1 |
Insertase YidC |
−1.2089 |
1.24E-05 |