Table 1.
Descriptive statistics of patients with a cancer diagnosis stratified according to mCA status.
| Characteristic | N | Overall, N = 48,919a | No mCA, N = 38,849a | Any mCA, N = 10,070a | P b |
|---|---|---|---|---|---|
| Age at bsl | 48,919 | <0.001 | |||
| N | 48,919 | 38,849 | 10,070 | ||
| N missing | 0 | 0 | 0 | ||
| Mean (SD) | 60 (7) | 60 (7) | 63 (5) | ||
| Median (IQR) | 62 (56, 65) | 61 (55, 65) | 64 (61, 67) | ||
| Range | 40, 71 | 40, 70 | 40, 71 | ||
| Men | 48,919 | 22,403 (45.8%) | 14,989 (38.6%) | 7,414 (73.6%) | <0.001 |
| Smoking status | 48,624 | <0.001 | |||
| Never smoker | 23,865 (49.1%) | 19,888 (51.5%) | 3,977 (39.7%) | ||
| Previous smoker | 19,274 (39.6%) | 14,755 (38.2%) | 4,519 (45.1%) | ||
| Current smoker | 5,485 (11.3%) | 3,970 (10.3%) | 1,515 (15.1%) | ||
| Unknown | 295 | 236 | 59 | ||
| Bladder cancer | 48,919 | 1,743 (3.6%) | 1,191 (3.1%) | 552 (5.5%) | <0.001 |
| Larynx cancer | 48,919 | 375 (0.8%) | 245 (0.6%) | 130 (1.3%) | <0.001 |
| Corpus uteri | 48,919 | 2,331 (4.8%) | 2,108 (5.4%) | 223 (2.2%) | <0.001 |
| Prostate cancer | 48,919 | 13,274 (27.1%) | 8,970 (23.1%) | 4,304 (42.7%) | <0.001 |
| Breast cancer | 48,919 | 17,304 (35.4%) | 15,678 (40.4%) | 1,626 (16.1%) | <0.001 |
| Rectal cancer | 48,919 | 2,268 (4.6%) | 1,731 (4.5%) | 537 (5.3%) | <0.001 |
| Kidney cancer | 48,919 | 1,910 (3.9%) | 1,472 (3.8%) | 438 (4.3%) | 0.010 |
| Non-Hodgkin lymphoma | 48,919 | 3,038 (6.2%) | 2,189 (5.6%) | 849 (8.4%) | <0.001 |
| Melanoma | 48,919 | 4,912 (10.0%) | 4,031 (10.4%) | 881 (8.7%) | <0.001 |
| Lung cancer | 48,919 | 4,215 (8.6%) | 3,074 (7.9%) | 1,141 (11.3%) | <0.001 |
| Chemotherapy | 48,919 | <0.001 | |||
| None | 37,512 (76.7%) | 29,610 (76.2%) | 7,902 (78.5%) | ||
| Yes | 11,407 (23.3%) | 9,239 (23.8%) | 2,168 (21.5%) | ||
| Radiotherapy | 48,919 | 0.036 | |||
| None | 45,846 (93.7%) | 36,454 (93.8%) | 9,392 (93.3%) | ||
| Yes | 3,073 (6.3%) | 2,395 (6.2%) | 678 (6.7%) | ||
| Prevalent hypertension | 48,919 | 6,077 (12.4%) | 4,569 (11.8%) | 1,508 (15.0%) | <0.001 |
| Autosomal mCA | 48,919 | <0.001 | |||
| Ref. | 46,487 (95.0%) | 38,849 (100.0%) | 7,638 (75.8%) | ||
| Autosomal | 2,432 (5.0%) | 0 (0.0%) | 2,432 (24.2%) | ||
| Loss of X | 48,919 | <0.001 | |||
| Ref. | 47,278 (96.6%) | 38,849 (100.0%) | 8,429 (83.7%) | ||
| Loss of X | 1,641 (3.4%) | 0 (0.0%) | 1,641 (16.3%) | ||
| Loss of Y | 48,919 | <0.001 | |||
| Ref. | 42,361 (86.6%) | 38,849 (100.0%) | 3,512 (34.9%) | ||
| Loss of Y | 6,558 (13.4%) | 0 (0.0%) | 6,558 (65.1%) | ||
| Expanded mCA | 48,919 | <0.001 | |||
| Ref. | 47,009 (96.1%) | 38,849 (100.0%) | 8,160 (81.0%) | ||
| Expanded mCA | 1,910 (3.9%) | 0 (0.0%) | 1,910 (19.0%) | ||
| Death of CVD causes | 48,919 | 813 (1.7%) | 550 (1.4%) | 263 (2.6%) | <0.001 |
| Death of CAD causes | 48,919 | 368 (0.8%) | 226 (0.6%) | 142 (1.4%) | <0.001 |
| Death from cancer | 48,919 | 8,433 (17.2%) | 6,254 (16.1%) | 2,179 (21.6%) | <0.001 |
| Death of any cause | 48,919 | 10,632 (21.7%) | 7,785 (20.0%) | 2,847 (28.3%) | <0.001 |
Abbreviations: bsl., baseline; IQR, interquartile range; Ref., referent category.
a n (%).
bWilcoxon rank sum test; Pearson χ2 test.