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. 2023 Feb 20;29(11):2066–2074. doi: 10.1158/1078-0432.CCR-22-2765

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©2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 2. Kaplan–Meier plot of OS in the tTMB-high (≥10 mut/Mb) and tTMB-low (<10 mut/Mb) subgroups for patients treated with durvalumab monotherapy (A) or with durvalumab plus tremelimumab (B) in HAWK/CONDOR. HRs were calculated as tTMB-high versus -low for each treatment group. CI, confidence interval; HR, hazard ratio; OS, overall survival; mut/Mb, mutations/megabase; tTMB, tissue tumor mutational burden — Kaplan–Meier plot of OS in the tTMB-high (≥10 mut/Mb) and tTMB-low (<10 mut/Mb) subgroups for patients treated with durvalumab monotherapy (A) or with durvalumab plus tremelimumab (B) in HAWK/CONDOR. HRs were calculated as tTMB-high versus -low for each treatment group. CI, confidence interval; HR, hazard ratio; OS, overall survival; mut/Mb, mutations/megabase; tTMB, tissue tumor mutational burden