Table 3. Association of Cortical Measures With Gestational Age and the SIMDa.
| Cortical measure | Standardized β coefficient (95% CI) | P value | |
|---|---|---|---|
| Raw | BH corrected | ||
| Gestational age | |||
| Mean cortical curvature | 0.01 (−0.07 to 0.09) | .75 | .75 |
| Mean cortical surface area | 0.10 (0.02 to 0.18) | .01 | .03 |
| Mean cortical thickness | −0.03 (−0.12 to 0.06) | .43 | .48 |
| Mean gyrification index | 0.16 (0.07 to 0.25) | <.001 | <.001 |
| Mean sulcal depth | 0.03 (−0.08-0.14) | .04 | .15 |
| SIMD | |||
| Mean cortical curvature | −0.05 (−0.15 to 0.06) | .37 | .46 |
| Mean cortical surface area | 0.05 (−0.05 to 0.16) | .29 | .46 |
| Mean cortical thickness | −0.05 (−0.18 to 0.08) | .36 | .46 |
| Mean gyrification index | 0.07 (−0.05 to 0.19) | .20 | .40 |
| Mean sulcal depth | 0.02 (−0.12 to 0.17) | .19 | .40 |
Abbreviations: BH, Benjamini Hochberg correction; SIMD, Scottish Index of Multiple Deprivation.
a
Fully adjusted ridge regression model, including gestation at birth, SIMD, gestation at magnetic resonance imaging scan, the interaction term (if applicable), birth weight z score, birth head circumference z score, sex, smoking in pregnancy, and breast milk at discharge. Corrected for false discovery rate.