Table 1. Intra-EC pairs for the three Na_v channels with known tertiary structure.

Name	Structure (PDB ID)	CA_Str	CA_DCA	N_Coin	N/DCA (%)	N_T10
“CA_Str” is the number of contact pairs in the tertiary structure; “CA_DCA” is the number of predicted pairs; “N_Coin” is the number that the predicted contact pairs do exist in 3D structure; “N/DCA” (N_Coin/CA_DCA) is the precision of prediction. “N_T10” is the number that the predicted contact pairs of top 10 ECs that do exist in 3D structure
NavAb	3rvy	539	52	32	61.538	8
NavRh	4dxw	603	50	31	62.000	8
NavPaS	5x0mA	1009	94	51	54.255	7
	5x0mB	661	54	28	51.851	6
	5x0mC	860	80	45	56.250	6
	5x0mD	675	52	36	69.230	7