Clifford 2005.
| Study characteristics | ||
| Methods |
Effect of a pharmaceutical care program on vascular risk factors in type 2 diabetes: the Fremantle Diabetes Study Patient RCT, conducted with adults from the Fremantle Diabetes Study, Australia Two arms: 1) Usual care (control arm) and 2) PC ‐ Pharmaceutical Care (intervention arm) |
|
| Participants | Control arm N: 99 Intervention arm N: 99 Diabetes type: type 2 Mean age: 70.4 ± 7.7 % Male: 52.3 Longest follow‐up: 12 months |
|
| Interventions |
Control arm: None Intervention arm: 1) Case management 2) Patient education 3) Promotion of self‐management |
|
| Outcomes | 1) Statins, N users (%) Control arm: pre 50 (57), post 52 (59) Intervention arm: pre 51 (55), post 54 (59) 2) Antihypertensives (any), N users (%) Control arm: pre 66 (75), post 74 (84) Intervention arm: pre 69 (75), post 81 (88) 3) HbA1c, median % (SD) Control arm: pre 7.1 (1.1), post 7.1 (NR) Intervention arm: pre 7.5 (0.9), post 7.0 (NR) 4) SBP, mean mmHg (SD) Control arm: pre 156.0 (25.0), post 149.0 (NR) Intervention arm: pre 157.0 (22.0), post 143.0 (NR) 5) DBP, mean mmHg (SD) Control arm: pre 77.0 (11.0), post 75.0 (NR) Intervention arm: pre 77.0 (10.0), post 72.0 (NR) |
|
| Funding source | The Raine Foundation, University of Western Australia, funded the FDS. R.M.C. was the recipient of a National Health and Medical Research Council of Australia PhD scholarship | |
| Notes | — | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | High risk | Consecutive allocation. |
| Allocation concealment (selection bias) | Unclear risk | Information not available. |
| Patient's baseline characteristics (selection bias) | High risk | Diabetes duration, etc. |
| Patient's baseline outcomes (selection bias) | High risk | Information not available. |
| Incomplete outcome data (attrition bias) | Low risk | Information not available. |
| Blinding of participants and personnel (performance bias) and of outcome assessors (detection bias) | Low risk | Information not available. |
| Selective reporting (reporting bias) | Low risk | Information not available. |
| Risk of contamination (other bias) | Unclear risk | Information not available. |
| Other bias | Low risk | Information not available. |