Tildesley 2010.

Study characteristics
Methods	Effect of internet therapeutic intervention on A1c levels in patients with type 2 diabetes treated with insulin Patient RCT. Setting not reported Two arms: 1. Usual care (control arm) and 2. Intervention (intervention arm)
Participants	Control arm N: 25 Intervention arm N: 25 Diabetes type: type 2 Mean age: NR ± NR % Male: NR Longest follow‐up: 6 months
Interventions	Control arm: 1) Facilitated relay of clinical information 2) Promotion of self‐management Intervention arm: 1) Facilitated relay of clinical information 2) Promotion of self‐management
Outcomes	1) HbA1c, mean % (SD) Control arm: pre 8.5 (1.2), post 8.4 (1.4) Intervention arm: pre 8.8 (1.3), post 7.6 (0.7)
Funding source	This work was supported by the Endocrine Research Society, Vancouver, British Columbia, which received funding from ALR Technologies
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer random number generator.
Allocation concealment (selection bias)	Unclear risk	Not described.
Patient's baseline characteristics (selection bias)	Low risk	Quote: "Baseline demographic and clinical characteristics were similar."
Patient's baseline outcomes (selection bias)	Low risk	HbA1c (P = 0.425).
Incomplete outcome data (attrition bias)	Low risk	Numbers lost to follow‐up were small and comparable between both groups.
Blinding of participants and personnel (performance bias) and of outcome assessors (detection bias)	Unclear risk	Blinding not described, HbA1c objective laboratory methods not described.
Selective reporting (reporting bias)	Low risk	Outcomes match those listed in the protocol.
Risk of contamination (other bias)	Low risk	Information not available.
Other bias	Low risk	Information not available.