Table 2.
Comparison of ICU patients along all-cause mortality
| Overall, (N = 92) | Survivors, (N = 72) | Non-survivors, (N = 20) | p value | |
|---|---|---|---|---|
| Age, years | 67 (58, 74) | 66 (57, 72) | 74 (60, 76) | 0.2 |
| Unknown | 23 | 18 | 5 | |
| Gender, n (%) | ||||
| Female | 41 (59) | 33 (61) | 8 (53) | 0.6 |
| Male | 28 (41) | 21 (39) | 7 (47) | |
| Unknown | 23 | 18 | 5 | |
| Metformin doses, mg/days | 2,500 (1,700, 3,000) | 2,550 (1,700, 3,000) | 1,700 (1,700, 1,700) | 0.007 |
| Unknown | 45 | 36 | 9 | |
| Metformin concentration, µg/mL (plasma/serum) | 53 (14, 69) | 55 (36, 70) | 29 (2, 62) | 0.2 |
| Unknown | 53 | 43 | 10 | |
| Creatinine (median), µmol/L (plasma/serum) | 528 (277, 799) | 589 (371, 824) | 313 (191, 624) | 0.024 |
| Arterial pH | 6.93 (6.80, 7.12) | 6.95 (6.80, 7.12) | 6.89 (6.80, 7.13) | 0.6 |
| Lactate (median), mmol/L | 16 (12, 21) | 16 (12, 21) | 17 (13, 24) | 0.2 |
| Bicarbonate, mmol/L | 5.0 (3.0, 9.3) | 5.0 (3.0, 8.7) | 6.0 (4.9, 8.4) | 0.5 |
| Unknown | 50 | 37 | 13 | |
| Acute renal impairment, n (%) | ||||
| No | 20 (34) | 10 (23) | 10 (71) | 0.002 |
| Yes | 38 (66) | 34 (77) | 4 (29) | |
| Unknown | 34 | 28 | 6 | |
| Diarrhea/vomiting days before admission, n (%) | ||||
| No | 23 (50) | 13 (37) | 10 (91) | 0.002 |
| Yes | 23 (50) | 22 (63) | 1 (9.1) | |
| Unknown | 46 | 37 | 9 | |
| Chronic renal impairment, n (%) | ||||
| No | 39 (75) | 30 (79) | 9 (64) | 0.3 |
| Yes | 13 (25) | 8 (21) | 5 (36) | |
| Unknown | 40 | 34 | 6 | |
| Liver impairment/alcoholism, n (%) | ||||
| No | 32 (76) | 23 (77) | 9 (75) | >0.9 |
| Yes | 10 (24) | 7 (23) | 3 (25) | |
| Unknown | 50 | 42 | 8 | |
| Infection, n (%) | ||||
| No | 24 (59) | 16 (57) | 8 (62) | >0.9 |
| Yes | 17 (41) | 12 (43) | 5 (38) | |
| Unknown | 51 | 44 | 7 | |
| Other reasons for hypoxia, n (%) | ||||
| No | 28 (56) | 22 (59) | 6 (46) | 0.5 |
| Yes | 22 (44) | 15 (41) | 7 (54) | |
| Unknown | 42 | 35 | 7 |